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NAQC Newsroom: Research

The Sociopharmacology of Tobacco Addiction: Implications for Understanding Health Disparities.

Friday, September 11, 2015  
Posted by: Natalia Gromov
Adam M. Leventhal
The Sociopharmacology of Tobacco Addiction: Implications for Understanding Health Disparities.
Nicotine Tob Res published 18 April 2015, 10.1093/ntr/ntv084
Efforts to reduce the public health burden of tobacco use have not equally benefited all members of society, leading to disparities in tobacco use as a function of ethnicity/race, socioeconomic position, physical/behavioral comorbidity, and other factors. Although multi-level transdisciplinary models are needed to comprehensively understand sources of tobacco-related health disparities (TRHD), the incorporation of psychopharmacology into TRHD research is virtually absent. Similarly, psychopharmacology researchers have often overlooked the societal context in which tobacco is consumed. In an effort to facilitate transdisciplinary research agendas for studying TRHD and the psychopharmacology of tobacco use, this paper introduces a novel paradigm, called “sociopharmacology.” Sociopharmacology is a platform for investigating how contextual factors amplify psychopharmacological determinants of smoking to disproportionately enhance vulnerability to smoking in populations subject to TRHD. The overall goal of sociopharmacology is to identify proximal person-level psychopharmacological mechanisms that channel distal societal-level influences on TRHD. In this paper I describe: (1) sociopharmacology’s overarching methodology and theoretical framework; (2) example models that apply sociopharmacology to understand mechanisms underlying TRHD; and (3) how sociopharmacological approaches may enhance the public health impact of basic research on the psychopharmacology of tobacco use; and (4) how understanding sociopharmacological mechanisms of TRHD might ultimately translate into interventions that reduce TRHD.

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